Paroxysmal Nocturnal Hemoglobinuria and Related Disorders Molecular Aspects of Pathogenesis

Discussion in 'E-Books & Tutorials' started by Bo0mB0omh, Feb 11, 2019.

  1. Bo0mB0omh

    Bo0mB0omh Well-Known Member

    Joined:
    Nov 20, 2018
    Messages:
    43,144
    Likes Received:
    2
    Gender:
    Female
    [​IMG]

    Paroxysmal Nocturnal Hemoglobinuria and Related Disorders: Molecular Aspects of Pathogenesis By Taroh Kinoshita (auth.), Mitsuhiro Omine M.D., Taroh Kinoshita Ph.D. (eds.)
    2003 | 285 Pages | ISBN: 4431680047 | PDF | 104 MB

    Few publications focus on the mysterious, genetically acquired disease paroxysmal nocturnal hemoglobinuria (PNH) and the related "intractable" disorders-aplastic anemia and myelodysplastic syndromes. Now, however, the latest understanding of the clinical and molecular genetic aspects of PNH is summarized here in the proceedings of the International Symposium held in Tokyo in 2001. Major topics reviewed include the molecular mechanisms of the PIG-A gene mutation; complement activation and inhibitors; experimental animal models; pathogenesis; the history of PNH research; the natural history of the disease; the mechanism of PNH clone expansion; the emergence of PNH clones under bone marrow failure syndromes; and treatment of the disease by immunosuppressive agents and stem cell transplantation. This book provides an invaluable summary of current research on the fundamental aspects of PNH pathology, presented by renowned experts in the field.
    DOWNLOAD
    (Buy premium account for maximum speed and resuming ability)

    Code:
    https://rapidgator.net/file/8237d1e71e8c33a5a3715a65d0333a4f/39nwz.rar
    
    Code:
    http://turbobit.net/e368p3q55dlm/39nwz.rar.html